Uses & Treatments:
Devolsteron (Covinan)
Temporary postponement of heat:
A single injection given at any time in anoestrus but preferably not more than one month before the effect is required.
The subsequent oestrus will occur on average 6 months after the injection.
In about 3% of cases the interval will be shorter than 3 months and in up to 4% of bitches the delay will be longer than 12 months.
Suppression of heat:
A single injection as soon as possible after the onset of pro-oestrus is seen.
Following the injection,
bleeding,
vulval swelling and attractiveness to dogs should gradually decrease and stop within 5–7 days.
The time for return to oestrus in the majority of bitches will be 5–6 months on average,
but in approximately 3% of bitches the interval will be shorter than 3 months and in 1% it will be longer than 12 months.
Treatment of false pregnancy:
A single dose, given preferably as soon as the signs are seen.
In most cases nervous signs will disappear within 6 days and lactation will have stopped or be much reduced by day 9 after injection.
In approximately 20% of cases the signs will recur within one month of treatment,
about 70% of these cases will respond to a second dose.
Prevention of false pregnancy:
Medication for permanent postponement of oestrus as advocated above.
Oestrus control:
Dosage regimes similar to those given for bitches are advised for permanent postponement,
temporary postponement or the suppression of calling,
except that for temporary postponement of calling the injections may be given in either dioestrus or anoestrus.
Following injection at the onset of calling,
the signs will usually abate within 1–4 days,
but in a few cases such a response may not be seen for 7 days.
As cats are seasonally polyoestrus,
the recurrence of calling after treatment is very variable.
However in one study 11% and 30% of cats called within 5 months after medication in anoestrus and pro-oestrus respectively.
The return to calling will be further delayed if the non breeding season (anoestrus) intervenes.
Treatment and prevention of feline miliary dermatitis:
A single injection is often sufficient but a second dose may be given 14 days later if the clinical response is not adequate.
Dosing may need to be repeated 4 monthly,
or more frequently if necessary depending on the clinical response obtained.
Jills:
Oestrus control:
Delvosteron (COVINAN) can be used to suppress or postpone heat in jills during the breeding season usually March to September.
Following injection in jills showing prolonged oestrus (suppression) the signs will usually abate (pass) within 10–11 days.
Injections given just before the onset of the breeding season (postponement),
or during the breeding season (suppression or postponement),
will usually maintain the jill in anoestrus for the remainder of the breeding season.
Singestar
Singestar ® MP is indicated to prevent the maturation of ovarian follicles,
marked anti-estrogenic effects,
of the anti androgenic,
and androgen varieties (to prevent or postpone the female cycle)
Specific to postpone the estrus,
(This treatment does not replace it),
As with any postponed estrus, the condition of the animal does not replace an ovarion hysterectomy.
For the treatment of or deviation in dimorphism own behaviour, dimorphism sex, such as aggression between males.
To abate sexual aggression among Jills,(domestic rodents) and continuous riding, marking territory, continuous mating, etc, in domestic pets.